The temperature regulation of the spontaneous activity frequency and the concomitant changes of the cortical neurons' spike amplitude

In the sensorimotor cortical slices of guinea pigs, the rate of neurons' spike activity increased at 27-29 and 34-36 degrees C. The change of the firing rate was accompanied by a drop in the spike amplitude at the temperature below 27 and above 34 degrees C. Usually after cooling to 24 degrees...

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Bibliographic Details
Published in:	Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Vol. 96; no. 3; p. 315
Main Authors:	Pasikova, N V, Mednikova, Iu S, Averina, I V
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-03-2010
Subjects:	Animals Cell Membrane Permeability - physiology Cerebral Cortex - physiology Guinea Pigs Hot Temperature Neurons - physiology Potassium - metabolism
Online Access:	Get more information
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Summary:	In the sensorimotor cortical slices of guinea pigs, the rate of neurons' spike activity increased at 27-29 and 34-36 degrees C. The change of the firing rate was accompanied by a drop in the spike amplitude at the temperature below 27 and above 34 degrees C. Usually after cooling to 24 degrees C the spike amplitude fully restored when the temperature increased to 32-34 degrees C. The fall of spike amplitude at t >35 degrees C could not be stopped by temperatyre decrease. The data obtained indicate the important role of the neuron membrane K+ permeability.
ISSN:	0869-8139