Surgical management of inflammatory granuloma which developed following subcutaneous injection of leuprorelin acetate: a case report

A case of granuloma which developed following a subcutaneous injection of leuprorelin acetate is presented. A prominent induration developed at the site of injection with a three-month type preparation, and radical retropubic prostatectomy and simultaneous excision of the granulomas were requested b...

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Bibliographic Details
Published in:	Hinyokika kiyo. Acta urologica Japonica Vol. 51; no. 7; p. 487
Main Authors:	Oida, Tomoyuki, Shichiri, Yasumasa, Takao, Noriyasu, Kanno, Toru, Kanamaru, Hiroshi
Format:	Journal Article
Language:	Japanese
Published:	Japan 01-07-2005
Subjects:	Aged Aged, 80 and over Antineoplastic Agents, Hormonal - administration & dosage Antineoplastic Agents, Hormonal - adverse effects Granuloma - chemically induced Granuloma - surgery Humans Inflammation - chemically induced Injections, Subcutaneous Leuprolide - administration & dosage Leuprolide - adverse effects Male Prostatic Neoplasms - drug therapy
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Summary:	A case of granuloma which developed following a subcutaneous injection of leuprorelin acetate is presented. A prominent induration developed at the site of injection with a three-month type preparation, and radical retropubic prostatectomy and simultaneous excision of the granulomas were requested by the patient since they were large, infectious and painful. Our experience may indicate the necessity of conversion from leuprorelin acetate to other drugs (e.g., goserelin acetate, castration) if a local induration, caused by a subcutaneous injection of leuprorelin acetate, has developed to a large granuloma.
ISSN:	0018-1994