Potentialities of current methods for laboratory analysis in the evaluation of the severity and prevalence of nephrolithiasis in Tajikistan

• Published in: Klinicheskaia laboratornaia diagnostika no. 11; p. 17
• Main Authors: Kadyrov, Z A, Nusratulloev, I, Suleĭmanov, S I, Istratov, V G, Ramishvili, V Sh, Kondakova, V I, Nizomov, D S, Saakian, A S, Pirnazarov, M, Kapsargin, F P
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01-11-2008
• Subjects: Adolescent; Adult; Aged; Biomarkers - urine; Clinical Chemistry Tests; Humans; Mass Spectrometry; Middle Aged; Nephrolithiasis - epidemiology; Nephrolithiasis - physiopathology; Nephrolithiasis - urine; Peptide Hydrolases - urine; Severity of Illness Index; Spectrophotometry, Atomic; Tajikistan - epidemiology; Young Adult; Tajikistan
• ISSN: 0869-2084

The investigation was undertaken to study a relationship between some biogeochemical and environmental factors and nephrolithiasis morbidity rates in the regions of Tajikistan. The paper presents the data of an integrated examination involving biochemical, chromatographic, and mass-spectrometric studies of 1180 patients aged 14 to 76 years who have been treated at the Dushanbe Urology Medical Center. The investigation established a relationship of an increase in ICD morbidity in poor environmental regions of the Republic of Tajikistan to the high organic and non-organic pollution, the high natural mineralization and hardness of water, and the elevated levels of chlorides, sulfates, and other salt components, which in turn influences the severity of a pathological process.