Lung protection with anesthetics

Common inhaled and intravenous anesthetics except the barbiturate are recommended for the patients with bronco-constrictive lung disease because of their bronco-dilating property. However there are pharmacological potency differences between individual anesthetics. The halogenated inhaled anesthetic...

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Bibliographic Details
Published in:	Masui. The Japanese journal of anesthesiology Vol. 55; no. 5; p. 560
Main Authors:	Ishibe, Yuichi, Mochida, Shinsuke, Funaki, Kazumi
Format:	Journal Article
Language:	Japanese
Published:	Japan 01-05-2006
Subjects:	Anesthetics - pharmacology Anesthetics, Inhalation - pharmacology Anesthetics, Intravenous - pharmacology Animals Humans Lung - drug effects Lung - pathology Lung Diseases - complications Protective Agents - pharmacology Pulmonary Disease, Chronic Obstructive - physiopathology Reperfusion Injury - etiology Reperfusion Injury - prevention & control Respiration, Artificial - adverse effects Respiratory Distress Syndrome, Adult - etiology
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Summary:	Common inhaled and intravenous anesthetics except the barbiturate are recommended for the patients with bronco-constrictive lung disease because of their bronco-dilating property. However there are pharmacological potency differences between individual anesthetics. The halogenated inhaled anesthetics and propofol exert antiinflammatory effect on acute lung injury and acute respiratory distress syndrome in the laboratory level, but further study is required for future clinical application. These anesthetics also have an organ protective effect on the ischemia reperfusion lung injury, and their clinical application is expected in the lung transplantation surgery.
ISSN:	0021-4892