The fibrinolytic enzyme system in pregnancy in Nigerians

Results of a detailed study of the fibrinolytic enzyme system in pregnant and non-pregnant Nigerians are reported. It was observed that plasma plasminogen, alpha 1-antitrypsin, and alpha 2-macroglobulin were significantly increased in pregnancy (P less than 0.001) in comparison with the non-pregnant...

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Bibliographic Details
Published in:	African journal of medicine and medical sciences Vol. 18; no. 2; p. 89
Main Authors:	Akinsete, I, Uyanwah, P O
Format:	Journal Article
Language:	English
Published:	Nigeria 01-06-1989
Subjects:	Adult alpha 1-Antitrypsin - analysis alpha-Macroglobulins - analysis Female Fibrinolysis Humans Nigeria Plasminogen - analysis Pregnancy - blood Whole Blood Coagulation Time Nigeria
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Summary:	Results of a detailed study of the fibrinolytic enzyme system in pregnant and non-pregnant Nigerians are reported. It was observed that plasma plasminogen, alpha 1-antitrypsin, and alpha 2-macroglobulin were significantly increased in pregnancy (P less than 0.001) in comparison with the non-pregnant state. Fibrinogen was also increased but at a level of P less than 0.01. A prolonged euglobulin clot lysis time was also observed (P less than 0.001). There was no significant difference in the mean values of platelet count in the two groups. These findings indicate that Nigerian women in pregnancy show physiological changes in haemostasis identical to those reported in Caucasians.
ISSN:	0309-3913