Study on carcinogenic activity of several nickel compounds in mice

This paper reports the result of the tumor in site induced by several nickel compounds in mice. Three nickel compounds (Ni3S2, NiCl, pure nickel powder) were injected separately to the right arm pit subcutaneously (5 mg/mouse). At the end of the 62nd week, the tested mice were sacrificed. Only nicke...

Full description

Saved in:

Bibliographic Details
Published in:	Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao Vol. 20; no. 3; p. 307
Main Authors:	Wang, C J, Jiang, J H, Li, Y Q, Deng, S L, Luo, D Y, Xiao, H Y
Format:	Journal Article
Language:	Chinese
Published:	China 01-09-1989
Subjects:	Animals Female Fibrosarcoma - chemically induced Injections, Subcutaneous Male Mice Neoplasms, Experimental - chemically induced Nickel - toxicity
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	This paper reports the result of the tumor in site induced by several nickel compounds in mice. Three nickel compounds (Ni3S2, NiCl, pure nickel powder) were injected separately to the right arm pit subcutaneously (5 mg/mouse). At the end of the 62nd week, the tested mice were sacrificed. Only nickel sulfide induced tumors in the site of injection, the incidence of tumor was 36%. The majority of the tumors were fibrosarcomas, only 2 rhabdomyosarcomas. The tumors might infiltrate into the surrounding tissues, a few metastasized to the liver and/or the lungs.
ISSN:	0257-7712