Vertical transmission of HBsAg in Alexandria

A total of 735 pregnant women at delivery and their babies were screened for HBsAg to assess the vertical transmission of HB virus infection. The carrier rate among pregnant women was 5%, evidence of intrauterine transmission reached 8.1% and that of perinatal transmission was 33.3% The most importa...

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Bibliographic Details
Published in:	Journal of the Egyptian Public Health Association Vol. 65; no. 3-4; p. 377
Main Authors:	Farghaly, A G, Hassan, E M, Gawish, S, Kotkat, A
Format:	Journal Article
Language:	English
Published:	England 1990
Subjects:	Carrier State - immunology Female Fetal Blood - immunology Hepatitis B - immunology Hepatitis B - transmission Hepatitis B Surface Antigens - blood Humans Infant, Newborn Pregnancy Pregnancy Complications, Infectious - immunology
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Summary:	A total of 735 pregnant women at delivery and their babies were screened for HBsAg to assess the vertical transmission of HB virus infection. The carrier rate among pregnant women was 5%, evidence of intrauterine transmission reached 8.1% and that of perinatal transmission was 33.3% The most important factors affecting the carrier rate in mothers were the social class, parity, injections, dental manipulation and hospitalization. Nevertheless, among the factors increasing the rate of materno-fetal transmission were the presence of "e" Ag, high titer of HBsAg in mothers serum, cord blood antigenaemia, age of the mother, prolonged duration of labour and breast-feeding.
ISSN:	0013-2446