Pentose-phosphate shunt activity and red blood cell malonyldialdehyde levels in haemodialysis and in CAPD patients

The baseline concentrations of MDA in the RBC membranes and the MDA production in the erythrocytes following stimulation with ascorbate and cyanide are compared in a group of uraemic patients on chronic haemodialysis and in one treated with CAPD. Lower baseline concentrations and smaller production...

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Bibliographic Details
Published in:	Life support systems : the journal of the European Society for Artificial Organs Vol. 3 Suppl 1; p. 121
Main Authors:	Taccone-Gallucci, M, Giardini, O, Lubrano, R, Mazzarella, V, Bandino, D, Meloni, C, Elli, M, Citti, F, Cozzari, M, Buoncristiani, U
Format:	Journal Article
Language:	English
Published:	England 1985
Subjects:	Adolescent Adult Ascorbic Acid - pharmacology Child Cyanides - pharmacology Erythrocytes - drug effects Erythrocytes - metabolism Female Humans In Vitro Techniques Male Malonates - blood Malondialdehyde - blood Middle Aged Pentose Phosphate Pathway Peritoneal Dialysis, Continuous Ambulatory - adverse effects Renal Dialysis - adverse effects Uremia - blood Uremia - therapy
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Summary:	The baseline concentrations of MDA in the RBC membranes and the MDA production in the erythrocytes following stimulation with ascorbate and cyanide are compared in a group of uraemic patients on chronic haemodialysis and in one treated with CAPD. Lower baseline concentrations and smaller production of MDA following in vitro stimulation, point to a better function of the pentose-phosphate shunt in CAPD patients than in haemodialysis.
ISSN:	0261-989X