A new administration form of the nasal decongestant oxymetazoline: a study on the change of ostial patency in healthy individuals

A new administration form of the nasal decongestant oxymetazoline and the effect on patency of the maxillary ostium was investigated in five healthy volunteers. Registration and comparison of the equivalent diameter after administration of placebo spray and oxymetazoline spray, placebo solution and...

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Bibliographic Details
Published in:	Rhinology Vol. 32; no. 2; p. 78
Main Authors:	Jannert, M, Fryksmark, U, Ackerhans, M, Nilson, K
Format:	Journal Article
Language:	English
Published:	Netherlands 01-06-1994
Subjects:	Administration, Inhalation Aerosols Cross-Over Studies Equipment Design Female Humans Male Maxillary Sinus - drug effects Maxillary Sinus - physiology Nebulizers and Vaporizers Oxymetazoline - administration & dosage Oxymetazoline - pharmacology
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Summary:	A new administration form of the nasal decongestant oxymetazoline and the effect on patency of the maxillary ostium was investigated in five healthy volunteers. Registration and comparison of the equivalent diameter after administration of placebo spray and oxymetazoline spray, placebo solution and oxymetazoline solution were performed. It is our impression that administration of solution with the new spring-bellows container compared to spray oxymetazoline, is a more effective way of increasing the equivalent diameter of the maxillary ostium.
ISSN:	0300-0729