Brain ischemia

The sensitivity of MRI to changes in water state and volume makes it the most desirable modality for imaging early brain ischemia. Its sensitivity is reflected in the ability to show ischemic changes in the white matter of the asymptomatic elderly, which are attributed to axonal loss, demyelination,...

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Bibliographic Details
Published in:	Topics in magnetic resonance imaging Vol. 2; no. 1; pp. 63 - 75
Main Authors:	Virapongse, C, Brown, E, Malat, J
Format:	Journal Article
Language:	English
Published:	United States 01-12-1989
Subjects:	Aged Brain Ischemia - diagnosis Brain Ischemia - physiopathology Cerebral Infarction - diagnosis Cerebrovascular Circulation - physiology Contrast Media Gadolinium Gadolinium DTPA Humans Infant Magnetic Resonance Imaging Organometallic Compounds Pentetic Acid
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Summary:	The sensitivity of MRI to changes in water state and volume makes it the most desirable modality for imaging early brain ischemia. Its sensitivity is reflected in the ability to show ischemic changes in the white matter of the asymptomatic elderly, which are attributed to axonal loss, demyelination, and gliosis. In large infarcts, however, contrast enhancement with Gd-DTPA can be used to add specificity, should doubt exist as to the proper diagnosis. The ability of MR to image flow is a valuable adjunct, and MR angiography has the potential partially to replace invasive angiography. Applications of MR such as diffusion-perfusion studies, sodium imaging, and spectroscopy could all prove to be useful in the future.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0899-3459