Synthesis of some 2-benzoxazolinone derivatives and their analgesic properties

In this study, the synthesis and analgesic activities of some new 6-acyl-3-(4-substituted benzoylmethyl)-2-benzoxazolinone derivatives are reported. Their structures were confirmed by microanalysis, IR, and NMR spectral analysis. The obtained compounds were screened for their analgesic activities. A...

Full description

Saved in:

Bibliographic Details
Published in:	Bollettino chimico farmaceutico Vol. 136; no. 8; p. 545
Main Authors:	Erdogan, H, Eriskon, S, Demirdamar, R
Format:	Journal Article
Language:	English
Published:	Italy 01-09-1997
Subjects:	Analgesics, Non-Narcotic - chemical synthesis Analgesics, Non-Narcotic - pharmacology Animals Benzoxazoles - chemical synthesis Benzoxazoles - pharmacology Crystallization Female Mice
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	In this study, the synthesis and analgesic activities of some new 6-acyl-3-(4-substituted benzoylmethyl)-2-benzoxazolinone derivatives are reported. Their structures were confirmed by microanalysis, IR, and NMR spectral analysis. The obtained compounds were screened for their analgesic activities. Analgesic activity of these compounds was investigated by modified Koster Test. The 11 compounds synthesized showed good analgesic activities.
ISSN:	0006-6648