The enzymatic status of circulating lymphocytes as an index of the regenerative process in the lungs under stimulation with pyrimidine and purine derivatives. A clinical experimental study

Enzyme activities in the circulating lymphocytes permit to judge the character of the regenerative process in the lung, and the severity of the patient's condition; it helps in estimating the prognosis and in evaluating the efficacy of the applied therapy. Potassium orotate and Riboxin intensif...

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Bibliographic Details
Published in:	Haematologia Vol. 15; no. 1; p. 71
Main Authors:	Bilich, G L, Nazarova, L V, Sungurova, E V
Format:	Journal Article
Language:	English
Published:	Netherlands 1982
Subjects:	Acid Phosphatase - blood Alkaline Phosphatase - blood Animals Glycerolphosphate Dehydrogenase - blood Humans Hypertrophy - enzymology Inflammation - drug therapy Inosine Diphosphate - pharmacology Inosine Diphosphate - therapeutic use L-Lactate Dehydrogenase - blood Lung - pathology Lung - physiology Lymphocyte Activation - drug effects Lymphocytes - enzymology Male Neutrophils - enzymology Orotic Acid - pharmacology Orotic Acid - therapeutic use Purines - pharmacology Purines - therapeutic use Pyrimidines - pharmacology Pyrimidines - therapeutic use Rats Regeneration - drug effects Succinate Dehydrogenase - blood Uracil - analogs & derivatives Uracil - therapeutic use
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Summary:	Enzyme activities in the circulating lymphocytes permit to judge the character of the regenerative process in the lung, and the severity of the patient's condition; it helps in estimating the prognosis and in evaluating the efficacy of the applied therapy. Potassium orotate and Riboxin intensify the regenerative process in the lung undergoing a compensatory-hypertrophic rearrangement, and enhance the functional activity of circulating lymphocytes as participants of the regenerative process and stimulate the oxidation-reduction processes in lymphocytes.
ISSN:	0017-6559