Clinical trial with CIBA 1906 in lepromatous leprosy

Drug trial with CIBA 1906 was conducted in 50 cases of lepromatous leprosy who were intolerant to dapsone therapy. Drug was tolerated well and lepra reactions were infrequent and mild. Clinical improvement was seen in 72% cases whereas no appreciable change was detected in 28% cases. An average redu...

Full description

Saved in:

Bibliographic Details
Published in:	Leprosy in India Vol. 53; no. 2; p. 278
Main Authors:	Anand, L C, Tiwari, V D, Rathore, B S, Singh, O
Format:	Journal Article
Language:	English
Published:	India 01-04-1981
Subjects:	Adult Clinical Trials as Topic Humans Leprostatic Agents - therapeutic use Leprosy - drug therapy Male Phenylthiourea - adverse effects Phenylthiourea - analogs & derivatives Phenylthiourea - therapeutic use
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Drug trial with CIBA 1906 was conducted in 50 cases of lepromatous leprosy who were intolerant to dapsone therapy. Drug was tolerated well and lepra reactions were infrequent and mild. Clinical improvement was seen in 72% cases whereas no appreciable change was detected in 28% cases. An average reduction of 0.4 in BI was detected in 62% cases, while remaining cases did not show any reduction in BI. No significant side effects were encountered during the study. Antibacterial activity of CIBA 1906 was not found superior to dapsone.
ISSN:	0024-1024