Persistence of Australia antigen in leprosy--a frustrating puzzle in immunology

This paper deals with the relationship of Australia antigen (Au) to various sub-groups of leprosy, in a total of 200 cases. Au was found to be present up to 4% in lepromatous leprosy, 2% in tuberculoid leprosy and lepra reaction, and 3% of antibody in lepromatous leprosy. Presence of antibody denote...

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Bibliographic Details
Published in:	Leprosy in India Vol. 50; no. 1; p. 7
Main Authors:	Saoji, A M, Mene, A R
Format:	Journal Article
Language:	English
Published:	India 01-01-1978
Subjects:	Adolescent Adult Female Hepatitis B Surface Antigens Humans Leprosy - immunology Male
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Summary:	This paper deals with the relationship of Australia antigen (Au) to various sub-groups of leprosy, in a total of 200 cases. Au was found to be present up to 4% in lepromatous leprosy, 2% in tuberculoid leprosy and lepra reaction, and 3% of antibody in lepromatous leprosy. Presence of antibody denotes past antigenemia. The quantitation of the antigen is done using the new technique of Electro-immuno-diffusion (EID) of Laurell, synonymous with rocket technique. The persistence of the antigen is explained in the light of deranged immunological mechanisms.
ISSN:	0024-1024