Double primary germ cell tumor in a 45 year old woman: one case report and literature review

We report a rare case of double primary germ cell tumor: right ovarian yolk sac tumor and left ovarian dysgerminoma. A 45 year-old woman was admitted to our hospital due to irregular bleeding for 2 days and extended menstrual period. Right ovarian mass was discovered on transvaginal ultrasound. The...

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Bibliographic Details
Published in:	International journal of clinical and experimental pathology Vol. 14; no. 11; pp. 1090 - 1094
Main Authors:	Yang, Fan, Kang, Lin, Zhao, Huanfen
Format:	Journal Article
Language:	English
Published:	United States e-Century Publishing Corporation 01-01-2021
Subjects:	Case Report double primary tumor yolk sac tumor dysgerminoma Malignant germ cell tumor
Online Access:	Get full text
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Summary:	We report a rare case of double primary germ cell tumor: right ovarian yolk sac tumor and left ovarian dysgerminoma. A 45 year-old woman was admitted to our hospital due to irregular bleeding for 2 days and extended menstrual period. Right ovarian mass was discovered on transvaginal ultrasound. The pathology results revealed that right ovarian yolk sac tumor and left ovarian dysgerminoma. Total abdominal hysterectomy with bilateral salpingo-oophorectomy with debulking with pelvic lymphadenectomy was performed. The patient underwent adjuvant chemotherapy with BEP six courses in four months and AFP dropped from 8490 ng/ml to nearly 10 ng/ml. Conclusion: Total abdominal hysterectomy with bilateral salpingo-oophorectomy followed by combination chemotherapy must be the treatment of first choice of germ cell tumor.
ISSN:	1936-2625