General principles of vaccination under immunosuppression

The number of patients suffering from immunodeficiency is increasing; however, the vaccination rate of these patients is below average. Administration of inactivated vaccines is harmless but does not reliably trigger a persistent immune response. Live vaccines provide a reliable protection but can c...

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Bibliographic Details
Published in:	Zeitschrift für Rheumatologie Vol. 79; no. 9; p. 848
Main Authors:	Schreiner, D, Zepp, F
Format:	Journal Article
Language:	German
Published:	Germany 01-11-2020
Subjects:	Humans Immunization Schedule Immunocompromised Host Vaccination Vaccines, Combined Vaccines, inactivated Immunosuppression Vaccines, live, unattenuated Autoimmune diseases Vaccination
Online Access:	Get full text
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Summary:	The number of patients suffering from immunodeficiency is increasing; however, the vaccination rate of these patients is below average. Administration of inactivated vaccines is harmless but does not reliably trigger a persistent immune response. Live vaccines provide a reliable protection but can cause severe disease in immunocompromised patients. Live vaccines can be administered under defined levels of immunosuppression, e.g. against measles, mumps, rubella and varicella (MMRV). In addition, the immunization of the domestic environment plays an important role in preventing infectious diseases.
ISSN:	1435-1250
DOI:	10.1007/s00393-020-00891-3