Multicolor 19 F magnetic resonance imaging: A promising medical technique for in vivo visualization of multiple biological targets

• Published in: Fundamental research (Beijing) Vol. 3; no. 4; p. 529
• Main Authors: Jiang, Yuhang, Luo, Xiangjie, Chen, Limin, Lin, Hongyu, Gao, Jinhao
• Format: Journal Article
• Language: English
• Published: China 01-07-2023
• Subjects: Medical imaging technique; Multiplexed imaging; 19F magnetic resonance imaging; In vivo visualization; Multicolor 19F probes
• ISSN: 2667-3258
• DOI: 10.1016/j.fmre.2022.10.016

Driven by the needs of precision medicine, current imaging techniques are under continuous development to offer more accurate and comprehensive information beyond traditional macroscopic anatomical images. Multispectral color-coded (multicolor)
F magnetic resonance imaging (MRI) is receiving increasing attention owing to its capability for visualizing quantitative and multiplexed molecular information during various biological processes. The chemical design and preparation of
F probes lie at the core of multicolor
F MRI since their performance dominates the accomplishment of this technique. Herein, the working principles of multicolor
F MRI are briefly introduced. Recent progress on multicolor
F MRI probes for simultaneous
visualization of multiple biological targets is summarized. Finally, current challenges and potential solutions in this fast-developing field are discussed.