Letter: low population mortality from COVID-19 in countries south of latitude 35 degrees North supports vitamin D as a factor determining severity. Authors' reply

Letter: low population mortality from COVID-19 in countries south of latitude 35 degrees North supports vitamin D as a factor determining severity. Authors' reply

We thank Dr Mansur for his interest in our editorial in which we highlighted the association between northern latitude and increased COVID-19 mortality and for his helpful comments about the potential importance of vitamin D effects on cathelicidin and on the renin-angiotensin system, which could be...

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Bibliographic Details
Published in:Alimentary pharmacology & therapeutics
Main Authors: Rhodes, Jonathan M, Subramanian, Sreedhar, Laird, Eamon, Anne Kenny, Rose
Format: Journal Article
Language:English
Published: England 01-07-2020
Online Access:Get full text
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Summary:We thank Dr Mansur for his interest in our editorial in which we highlighted the association between northern latitude and increased COVID-19 mortality and for his helpful comments about the potential importance of vitamin D effects on cathelicidin and on the renin-angiotensin system, which could be important in protecting against severe COVID-19. Vitamin D is a secosteroid hormone, derived like cortisol and sex hormones from cholesterol, so not surprisingly it has a broad range of actions reflecting the several hundred or more genes that are vitamin D-responsive. .
ISSN:1365-2036
DOI:10.1111/apt.15823