Keratitis secondary to Fusarium spp. in Spain 2012-2014

• Published in: Archivos de la Sociedad Española de Oftalmología (English ed.) Vol. 93; no. 6; pp. 283 - 289
• Main Authors: Mosquera Gordillo, M A, Barón Cano, N, Garralda Luquin, A, López Gutiérrez, C, Mengual Verdú, E, Trujillo Cabrera, G, Garrido Fierro, J M, Lamarca Mateu, J, Sánchez España, J C, Marticorena Álvarez, P, Feijoó Lera, R, Martín Nalda, S, Marti Huguet, T, Gacía Conca, V
• Format: Journal Article
• Language: English; Spanish
• Published: 01-06-2018
• ISSN: 2173-5794
• DOI: 10.1016/j.oftal.2017.08.005

OBJECTIVETo describe the clinical-epidemiological characteristics of a case series of fungal keratitis associated with Fusarium spp.., in Spain during the years 2012 to 2014. METHODSA retrospective study of a case series was conducted on a systematic random sample of 10% of patients identified in Health Centres of provincial capitals (n=250). The centres were asked whether they had been presented with cases of Fusarium spp. keratitis characterised by microbiological methods. Of the 23 centres that responded, 14 had detected cases, with 13 of them accepting to participate, and 11 of them completing the study. The latter being sent a previously validated questionnaire. The variables analysed were: age, gender, habitual residence, profession, disease and medical history (previous systemic and ocular diseases, previous eye surgeries), and their outcomes. RESULTSThe response rate was 92%, identifying 23 cases of Fusarium spp.. of which 21 (91.3%) of them lived in urban areas. The professions most affected by the disease included chefs, administrative, and technical, with 13 cases (56.5%). The treatment guidelines established to confirm the infection showed the combined use of topical antibiotics associated with antiviral and/or antifungal agents. The use of contact lenses (86.9%) was the main risk factor. DISCUSSIONThis study showed that this is a rare disease in Spain, but that a large percentage of people who present with the disease are resident in urban areas, and they work in closed environments, focusing attention on microtraumas caused by use of contact lenses.