Coherent anti-Stokes Raman scattering rigid endoscope toward robot-assisted surgery

Label-free visualization of nerves and nervous plexuses will improve the preservation of neurological functions in nerve-sparing robot-assisted surgery. We have developed a coherent anti-Stokes Raman scattering (CARS) rigid endoscope to distinguish nerves from other tissues during surgery. The devel...

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Bibliographic Details
Published in:	Biomedical optics express Vol. 9; no. 2; pp. 387 - 396
Main Authors:	Hirose, K, Aoki, T, Furukawa, T, Fukushima, S, Niioka, H, Deguchi, S, Hashimoto, M
Format:	Journal Article
Language:	English
Published:	United States Optical Society of America 01-02-2018
Subjects:	(170.5660) Raman spectroscopy (170.0110) Imaging systems (170.2150) Endoscopic imaging (170.3890) Medical optics instrumentation
Online Access:	Get full text
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Summary:	Label-free visualization of nerves and nervous plexuses will improve the preservation of neurological functions in nerve-sparing robot-assisted surgery. We have developed a coherent anti-Stokes Raman scattering (CARS) rigid endoscope to distinguish nerves from other tissues during surgery. The developed endoscope, which has a tube with a diameter of 12 mm and a length of 270 mm, achieved 0.91% image distortion and 8.6% non-uniformity of CARS intensity in the whole field of view (650 μm diameter). We demonstrated CARS imaging of a rat sciatic nerve and visualization of the fine structure of nerve fibers.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2156-7085 2156-7085
DOI:	10.1364/BOE.9.000387