Methylprednisolone 투여 후 발생한 알레르기 반응

• Published in: Korean journal of anesthesiology Vol. 57; no. 4; pp. 499 - 502
• Main Authors: 정진헌, Jin Hun Chung, 안기량, Ki Ryang Ahn, 전혜정, Hye Jung Chun, 김천숙, Chun Sook Kim, 강규식, Kyu Sik Kang, 유시현, Sie Hyeon Yoo, 정지원, Ji Won Chung
• Format: Journal Article
• Language: Korean
• Published: 대한마취통증의학회(구 대한마취과학회) 30-10-2009; 대한마취통증의학회
• Subjects: Allergic reactions; Cardiopulmonary resuscitation; Corticosteroids; 마취과학
• ISSN: 2005-6419; 2005-7563

Corticosteroid preparations have anti-inflammatory and immunosuppressive properties and are used widely for the treatment of allergic disorders and asthma. Steroids themselves, however, can induce hypersensitivity reactions. In this study, we report the case of a 66-year-old man with chronic obstructive pulmonary disease who exhibited an allergic reaction (rash, bronchospasm, bradycardia, severe hypotension and cardiac arrest) immediately after the intravenous injection of methylprednisolone sodium succinate. Despite cardiopulmonary resuscitation, sinus rhythm was not restored. The anesthesiologist should be aware that allergic reactions to corticosteroids can occur. (Korean J Anesthesiol 2009;57:499∼502)