소아 마이코플라스마 폐렴의 다양한 임상 양상에 연관된 요인들

• Published in: Allergy asthma & respiratory disease pp. 357 - 361
• Main Authors: 김유나, 박철휘, 김수희, 유수진, 김효빈
• Format: Journal Article
• Language: Korean
• Published: 대한 소아알레르기 호흡기학회 30-12-2013
• Subjects: 소아과학
• ISSN: 2288-0402; 2288-0410

Purpose: Mycoplasma pneumonia (MP) is a major cause of community-acquired pneumonia in children and young adults. We aimed to investigate the factors that may influence on the clinical manifestations of MP in children.
Methods: A total of 109 admitted children from October 2011 to February 2012 were prospectively enrolled with physical examination and laboratory tests (complete blood count, C-reactive protein [CRP], and particle agglutinin assay). The diagnosis of MP was made when there was an infiltration on the chest X-ray and the particle agglutination test was once over 1:640 or showed 4-fold increase in serial tests. They were grouped by age, fever duration after treatment, presence of pleural effusion and wheezing.
Results: Preschool children showed shorter duration of fever (P=0.001), more wheezing (P<0.001), lower segmented neutrophil (P<0.001), and lower CRP levels (P=0.004) compared to schoolchildren. Prolonged fever (>3 days) and pleural effusion were developed in children with higher CRP (P=0.018 and P=0.007). Wheezing has been developed in children with younger age (P=0.007).
Conclusion: Younger age was a risk factor to develop wheezing in MP and prolonged fever and pleural effusion were more likely to develop in children with higher CRP. KCI Citation Count: 2