Selenium, thiobarbituric acid reactive substances, and thyroid hormone activation in broilers supplemented with selenium as selenized yeast or sodium selenite

• Published in: The Japanese journal of veterinary research Vol. 59; no. 2-3; pp. 69 - 77
• Main Authors: Valcić, Olivera, Jovanović, Ivan B, Milanović, Svetlana
• Format: Journal Article
• Language: English
• Published: Japan 01-08-2011
• Subjects: Animal Feed - analysis; Animal Nutritional Physiological Phenomena; Animals; Chickens - metabolism; Diet - veterinary; Dietary Supplements; Dose-Response Relationship, Drug; Glutathione Peroxidase - blood; Glutathione Peroxidase - metabolism; Lipid Peroxidation; Liver - metabolism; Selenium - administration & dosage; Selenium - metabolism; Selenium - pharmacology; Sodium Selenite - administration & dosage; Sodium Selenite - pharmacology; Thiobarbituric Acid Reactive Substances - metabolism; Thyroid Hormones - metabolism; Yeasts
• ISSN: 0047-1917

The objective of this experiment was to compare the efficiencies of sodium selenite (SS) and selenized yeast (SY) supplemented at different doses (0.05 and 0.30 mg Se/kg feed) with respect to plasma glutathione peroxidase (Gpx) activity, extent of oxidative lipid injury, and thyroid hormone activation in broilers during the first four weeks of growth. Results indicate a significant increase in plasma Gpx activity and reduction in thiobarbituric acid reactive substances (TBARS) in all supplemented groups at 4 weeks of age compared to 2-week-old chicks. Plasma thyronine activation was highest in SY supplemented broilers. It can be concluded that in the first 4 weeks of broiler life selenite has a more efficient antioxidative effect which is reflected in lower plasma and liver TBARS values. However, broiler feed supplementation with selenized yeast results in a more proficient conversion of T4 to T3.