Clinical evaluation of cefozopran in the field of surgery

Clinical evaluation of cefozopran in the field of surgery

We studied the clinical efficacy of cefozopran (CZOP), a newly developed injectable cephalosporin with a broad antibacterial spectrum, in surgical infections. The clinical efficacy was determined in 8 cases: cholangitis (1), localized peritonitis (2), subdiaphragmatic abscess (1), intraabdominal inf...

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Bibliographic Details
Published in:CHEMOTHERAPY Vol. 41; no. Supplement4; pp. 656 - 658
Main Authors: Matuno, Tuyoshi, Kamikawa, Yasuaki, Gouchi, Akira, Okanobu, Kouji, Orita, Kunzou
Format: Journal Article
Language:English
Japanese
Published: Japanese Society of Chemotherapy 1993
Subjects:
cefozopran
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Summary:We studied the clinical efficacy of cefozopran (CZOP), a newly developed injectable cephalosporin with a broad antibacterial spectrum, in surgical infections. The clinical efficacy was determined in 8 cases: cholangitis (1), localized peritonitis (2), subdiaphragmatic abscess (1), intraabdominal infection (1) and postoperative wound infection (3). CZOP was administered by intravenous drip infusion at a dose of 0.5-1 g twice daily for 3-11 days. The clinical efficacy was good in 4 patients, fair in 2 and poor in 2, showing an overall efficacy rate of 4/8. No adverse drug reactions or abnormal laboratory changes were observed.
ISSN:0009-3165
1884-5894
DOI:10.11250/chemotherapy1953.41.Supplement4_656