A case of steroid-dependent ulcerative colitis complicated by skin infection of Mycobacterium szulgai

• Published in: Nippon Shōkakibyō Gakkai zasshi Vol. 106; no. 9; p. 1359
• Main Authors: Hizawa, Kazuoki, Nagata, Yutaka, Kudo, Tetsuji, Taniguchi, Masahiko, Matsumoto, Takayuki, Iida, Mitsuo
• Format: Journal Article
• Language: Japanese
• Published: Japan 01-09-2009
• Subjects: Colitis, Ulcerative - complications; Colitis, Ulcerative - drug therapy; Humans; Male; Middle Aged; Mycobacterium Infections, Nontuberculous - complications; Mycobacterium Infections, Nontuberculous - drug therapy; Nontuberculous Mycobacteria; Prednisolone - therapeutic use; Skin Diseases, Bacterial - complications; Skin Diseases, Bacterial - drug therapy
• ISSN: 0446-6586
• DOI: 10.11405/nisshoshi.106.1359

We describe a case of a 47-year old Japanese man with steroid-dependent, refractory ulcerative colitis complicated by non-tuberculous mycobacterial skin infection. The patient remained in remission by combination therapy of 100mg azathioprine and 27.5mg prednisolone (total dose over 25g for three years), but developed a deep genital ulcer. Mycobacterium szulgai was confirmed by skin culture, and the ulcer became turned into a scar after oral administration of isoniazid, rifampicin, and ethanbutol.