Case report on the patient who showed a primary lung carcinoma accompanied with lung metastasis from renal cell carcinoma simultaneously during the clinical follow-up

• Published in: Nippon Hinyokika Gakkai zasshi Vol. 88; no. 10; p. 880
• Main Authors: Onishi, T, Ohishi, Y, Iizuka, N, Suzuki, H, Hosobe, T, Nakajo, H
• Format: Journal Article
• Language: Japanese
• Published: Japan 01-10-1997
• Subjects: Adenocarcinoma, Clear Cell - secondary; Carcinoma, Renal Cell - secondary; Carcinoma, Renal Cell - surgery; Humans; Kidney Neoplasms - pathology; Kidney Neoplasms - surgery; Lung Neoplasms - pathology; Lung Neoplasms - secondary; Male; Middle Aged
• ISSN: 0021-5287
• DOI: 10.5980/jpnjurol1989.88.880

We have studied on the patient who showed a primary lung carcinoma and microscopic metastasis from renal cell carcinoma simultaneously after nephrectomy for renal cell carcinoma.
A 57-year-old man who had an incidentally discovered right renal cell carcinoma at the time of the examination of different disease, and received nephrectomy. Two years and four months after nephrectomy, a solitary primary lung carcinoma was found. Therefore, he received lobectomy. Histopathological examination revealed that the lung tumour was a poorly differentiated adenocarcinoma, and peripheral lesions of the lung tumour, it was also discovered small clear-cell carcinoma simultaneously. At that time, we could not diagnose this carcinoma as a metastatic renal cell carcinoma. Nine months after lobectomy, new coin lesions were appeared in the lung. Therefore, we diagnosed a minimum clear lesion which was found nine months ago was metastatic renal cell carcinoma clinically. At present, the patient receives interferon-alpha therapy.
As a result, we diagnosed primary lung carcinoma and small metastatic renal cell carcinoma simultaneously. However, the latter diagnosis could be obtained through the progression of the disease.
We conclude that we must give heed to the patients with new cancerous lesions histologically when the patients treated of cancer previously.