Anti-ulcer effect of Nigella sativa Linn. against gastric ulcers in rats

Anti-ulcer effect of Nigella sativa Linn. against gastric ulcers in rats

The effect of alcoholic extract Of Nigella sativa was investigated in rats to evaluate the anti-ulcer activity by using two models, i.e. pyloric ligation and aspirininduced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, free acidity, total acidity...

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Bibliographic Details
Published in:Current science (Bangalore) Vol. 82; no. 2; pp. 177 - 179
Main Authors: Rajkapoor, B., Anandan, R., Jayakar, B.
Format: Journal Article
Language:English
Published: Current Science Association 25-01-2002
Subjects:
Acidity
Alcoholism
Antiulcer agents
Flavonoids
Gastric juice
Ligation
Pylorus
RESEARCH COMMUNICATIONS
Secretion
Stomach
Stomach ulcer
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Summary:The effect of alcoholic extract Of Nigella sativa was investigated in rats to evaluate the anti-ulcer activity by using two models, i.e. pyloric ligation and aspirininduced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decreases the volume of gastric acid secretion, free acidity, total acidity and ulcer index with respect to control.
ISSN:0011-3891