ANTIBACTERIAL ACTIVITY AND CLINICAL EVALUATION OF AM-715 IN THE FIELD OF UROLOGY

A new synthetic antibacterial agent, AM-715 was studied with respect to in vitro antibacterial activity and clinical effects in the urological field, and the following results were obtained. 1) Concerning MICs for clinically isolated 28 E. coli and 98 S. marcescens, AM-715 was more effective than NA...

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Published in:	CHEMOTHERAPY Vol. 29; no. Supplement4; pp. 420 - 433
Main Authors:	TOMINAGA, TAKASHI, TSUKADA, OSAMU, KISHI, HIROICHI, KAWABE, KAZUKI, NIIJIMA, TADAO, NISHIMURA, YOJI, MIYASHITA, ATSUSHI, SAITO, ISAO, ASANO, MICHIO, YUGE, JUNJI, MATSUMURA, TOSHIYUKI
Format:	Journal Article
Language:	Japanese
Published:	Japanese Society of Chemotherapy 25-12-1981
Online Access:	Get full text
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Summary:	A new synthetic antibacterial agent, AM-715 was studied with respect to in vitro antibacterial activity and clinical effects in the urological field, and the following results were obtained. 1) Concerning MICs for clinically isolated 28 E. coli and 98 S. marcescens, AM-715 was more effective than NA. 2) All of 77 patients withacute simple cystitis and two patients with acute simple pyelonephritis showed excellent or good response to AM-715 treatment. 3) Effectiveness rate for 33 patients with chronic complicated UTI was 73%. 4) Side effects were seen in 2 cases, one with stomatitis and the other with cheilitis. The case with cheilitis required cessation of administration of AM-715.
ISSN:	0009-3165 1884-5894
DOI:	10.11250/chemotherapy1953.29.Supplement4_420