Normalization of transcranial magnetic stimulation points by means of atlas registration

Transcranial magnetic stimulation (TMS) is a well-known technique to study brain function. Location of TMS points can be visualized on the subject's Magnetic Resonance Image (MRI). However inter-subject comparison is possible only after a normalization i.e. a transformation of the stimulation p...

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Bibliographic Details
Published in:2006 14th European Signal Processing Conference pp. 1 - 5
Main Authors: Zosso, D., Noirhomme, Q., Davare, M., Macq, B., Olivier, E., Thiran, J., De Craene, M.
Format: Conference Proceeding
Language:English
Published: IEEE 01-09-2006
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Summary:Transcranial magnetic stimulation (TMS) is a well-known technique to study brain function. Location of TMS points can be visualized on the subject's Magnetic Resonance Image (MRI). However inter-subject comparison is possible only after a normalization i.e. a transformation of the stimulation points to a reference atlas image. Here, we propose a generic and automatic image processing pipe-line for normalizing a collection of subjects' MRI and TMS points. The normalization uses a loop of rigid-transform followed by Basis-Splines registration. The used reference atlas is the common Montreal National Institute (MNI) brain atlas [2]. We show preliminary results from 10 subjects. Those normalized points were compared to the SPM normalization and validated by TMS experts.
ISSN:2219-5491
2219-5491