Structure and biological properties study of synthetic fibers nanocomposite coating for implantable materials

• Published in: 2017 IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering (EIConRus) pp. 91 - 94
• Main Authors: Zhurbinal, Natalia N., Gerasimenko, Alexander Yu, Suetina, Irina A., Mezentseva, Marina V., Pavlov, Alexander A.
• Format: Conference Proceeding
• Language: English
• Published: IEEE 2017
• Subjects: Animals; biological studies; Carbon nanotubes; coating; Coatings; knee ligaments implants; laser radiation; Nanobioscience; Nanomaterials; Surface treatment; Synthetic fibers
• DOI: 10.1109/EIConRus.2017.7910501

Composite nanocoating of synthetic fibers for implantable materials has been developed. The coating is intended to improve the adhesion and proliferation of biological cells, which can lead to a reduction in damaged tissue regeneration time after implantation of synthetic material in the human body. The basis of the coating is a dispersion of carbon nanotubes in the protein matrix. The coating was formed on the surface of synthetic fibers using ultrasonic waves and laser irradiation. Under the influence of the laser radiation electric field, there have been carried out evaporation of the water component of the dispersion and formation of the carbon nanotubes scaffold, which provides properties of the coating that promote cell attachment. The structure of coating was studied by atomic force microscopy. In vitro studies of interaction between nanocarbon coatings and biological cells of connective tissue were carried out. By scanning electron microscopy we showed the absence of the negative impact of carbon nanotubes on cell proliferation. Also toxicity studies of nanocoating have been conducted using white rat model. These studies showed no negative impact of synthetic fibers nanocoating on biological and morphological properties of the animal's tissues.