Occurrence of tetrodotoxin and anhydrotetrodotoxin in Vibrio sp. isolated from the intestines of a xanthid crab, Atergatis floridus

Vibrio sp. isolated from a xanthid crab, Atergatis floridus, was cultured, and tetrodotoxin (TTX) and anhydroTTX were indicated to be present in several fractions of the cell extract and the culture medium by reverse phase HPLC. The presence of the C9-base in alkaline hydrolyzates of these fractions...

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Bibliographic Details
Published in:	Journal of biochemistry (Tokyo) Vol. 99; no. 1; p. 311
Main Authors:	Noguchi, T, Jeon, J K, Arakawa, O, Sugita, H, Deguchi, Y, Shida, Y, Hashimoto, K
Format:	Journal Article
Language:	English
Published:	England 01-01-1986
Subjects:	Animals Brachyura - microbiology Chromatography, High Pressure Liquid Culture Media - analysis Hydrogen-Ion Concentration Intestines - microbiology Mass Spectrometry Tetrodotoxin - analogs & derivatives Tetrodotoxin - isolation & purification Vibrio - metabolism
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Summary:	Vibrio sp. isolated from a xanthid crab, Atergatis floridus, was cultured, and tetrodotoxin (TTX) and anhydroTTX were indicated to be present in several fractions of the cell extract and the culture medium by reverse phase HPLC. The presence of the C9-base in alkaline hydrolyzates of these fractions was confirmed by GC-MS and UV spectrometry. These results showed the production of TTX and anhydroTTX in the Vibrio sp., thus indicating one of the origins of TTX in nature.
ISSN:	0021-924X
DOI:	10.1093/oxfordjournals.jbchem.a135476