Epoxide Hydrolase-Catalyzed Enantioselective Synthesis of Chiral 1,2-Diols via Desymmetrization of meso-Epoxides

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Bibliographic Details
Published in:	Journal of the American Chemical Society Vol. 126; no. 36; pp. 11156 - 11157
Main Authors:	ZHAO, Lishan, HAN, Bin, HUANG, Zilin, MILLER, Mark, HUANG, Hongjun, MALASHOCK, Dan S., ZHU, Zuolin, MILAN, Aileen, ROBERTSON, Dan E., WEINER, David P., BURK, Mark J.
Format:	Journal Article
Language:	English
Published:	Washington, DC American Chemical Society 15-09-2004
Subjects:	Biological and medical sciences Chemical reactivity Chemistry Exact sciences and technology Fundamental and applied biological sciences. Psychology Mechanisms. Catalysis. Electron transfer. Models Molecular biophysics Organic chemistry Physical chemistry in biology Reactivity and mechanisms Catalytic reaction Enantioselectivity Enzyme Catalyst selectivity Three membered ring Enzymatic catalysis Experimental study Oxygen heterocycle Epoxide hydrolase Ring cleavage Ether hydrolases Hydrolases Catalyst activity
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Bibliography:	istex:9BF4E8222B928BA4ABF5C56E009BA538CDC4831C ark:/67375/TPS-PR90XBG1-M
ISSN:	0002-7863 1520-5126
DOI:	10.1021/ja0466210