RAPTOR: a fluoroimmunoassay-based fiber optic sensor for detection of food pathogens

• Published in: 2002 15th Optical Fiber Sensors Conference Technical Digest. OFS 2002(Cat. No.02EX533) pp. 249 - 252 vol.1
• Main Authors: Jung, C., McCrae, D.A., Saaski, E.W., DeMarco, D.R., Lim, D.V.
• Format: Conference Proceeding
• Language: English
• Published: IEEE 2002
• Subjects: Biomedical optical imaging; Fluorescence; Immune system; Laboratories; Optical detectors; Optical fiber sensors; Optical recording; Optical sensors; Optical waveguides; Pathogens
• ISBN: 0780372891; 9780780372894
• DOI: 10.1109/OFS.2002.1000548

This paper describes a portable, 4-channel fluorescence-based immunoassay system called "RAPTOR", which has been developed by Research International in conjunction with the Naval Research Laboratory. The RAPTOR represents a careful integration of optics, fluidics, electronics, and software into one compact system. This unit can automatically perform a user-defined, multi-step assay while simultaneously recording the signal from fluorescently-conjugated reporter antibodies as they bind to the surface of each of the system's four optical waveguides located in the disposable injection molded coupon. The RAPTOR can be used for high-sensitivity monitoring of biological agents and toxins in the lab or in the field.