Scintigraphic Localization of Lymphatic Leakage Site After Oral Administration of Iodine-123-IPPA

Chylothorax can occur secondary to traumatic lesions of the thoracic duct caused by chest injuries, surgical procedures involving the pleural space, neoplasms or malformations of the lymphatics. Lymphatic leakage sites were localized by scintigraphy after oral administration of the 123I-labeled long...

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Bibliographic Details
Published in:	The Journal of nuclear medicine (1978) Vol. 39; no. 12; pp. 2141 - 2144
Main Authors:	Kettner, Beatrice Ines, Aurisch, Reinhard, Ruckert, Jens Carsten, Sandrock, Dirk, Munz, Dieter Ludwig
Format:	Journal Article
Language:	English
Published:	Reston, VA Soc Nuclear Med 01-12-1998 Society of Nuclear Medicine
Subjects:	Administration, Oral Biological and medical sciences Child Chylothorax - diagnostic imaging Esophageal Neoplasms - surgery Humans Investigative techniques, diagnostic techniques (general aspects) Iodine Radioisotopes - administration & dosage Iodine Radioisotopes - pharmacokinetics Iodine Radioisotopes - therapeutic use Iodobenzenes - administration & dosage Iodobenzenes - pharmacokinetics Iodobenzenes - therapeutic use Lymph - secretion Lymphatic System - abnormalities Male Medical sciences Metabolic Clearance Rate Middle Aged Pleura Postoperative Complications Radionuclide Imaging Radionuclide investigations Respiratory system Tongue Neoplasms - surgery Radionuclide study Human Evaluation Effusion Radiolabelling Respiratory disease Indication Oral administration Scintigraphy Fatty acids Sensitivity Medical imagery Pleural disease Diagnosis Chylothorax Iodine
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Summary:	Chylothorax can occur secondary to traumatic lesions of the thoracic duct caused by chest injuries, surgical procedures involving the pleural space, neoplasms or malformations of the lymphatics. Lymphatic leakage sites were localized by scintigraphy after oral administration of the 123I-labeled long-chain fatty acid derivative iodophenyl pentadecanoic acid (IPPA). We report on three patients with different lymphatic leakage sites and on one normal control subject. IPPA scintigraphy localized the lymphatic leakage site correctly in all three patients. In two of them, the method even guided the successful surgical treatment of the leakage. This approach is suitable for detecting lymphatic leakages of intestinal origin.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0161-5505 1535-5667