Phagocytosis of chrysotile fibers by pleural mesothelial cells in culture

Phagocytosis of chrysotile fibers by pleural mesothelial cells in culture

Pleural mesothelial cells (PMC) from the parietal pleura of rats were incubated in culture with UICC A chrysotile fibers. The sequence of events in phagocytosis was studied by electron microscopy: phases of attachment sequestration, and degranulation of lysosomal content into the phagocytic vacuole...

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Bibliographic Details
Published in:The American journal of pathology Vol. 94; no. 3; pp. 529 - 538
Main Authors: Jaurand, MC, Kaplan, H, Thiollet, J, Pinchon, MC, Bernaudin, JF, Bignon, J
Format: Journal Article
Language:English
Published: United States ASIP 01-03-1979
Subjects:
Animals
Asbestos
Cells, Cultured
Epithelial Cells
Microscopy, Electron
Phagocytosis
Pleura - cytology
Rats
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Summary:Pleural mesothelial cells (PMC) from the parietal pleura of rats were incubated in culture with UICC A chrysotile fibers. The sequence of events in phagocytosis was studied by electron microscopy: phases of attachment sequestration, and degranulation of lysosomal content into the phagocytic vacuole were observed. This demonstrates that PMC can engage in phagocytosis of chrysotile fibers.
ISSN:0002-9440
1525-2191