Clinical results after cardiac valve replacement with the Sorin prosthesis. A 6-year experience

• Published in: European journal of cardio-thoracic surgery Vol. 2; no. 5; pp. 355 - 359
• Main Authors: COTRUFO, M, FESTA, M, RENZULLI, A, DE LUCA, L, SANTE, P, GIANNOLO, B
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Science B.V 1988; Elsevier Science
• Subjects: Adolescent; Adult; Aged; Anticoagulants - adverse effects; Aortic Valve - surgery; Biological and medical sciences; Cardiology. Vascular system; Child; Child, Preschool; Echocardiography; Endocardial and cardiac valvular diseases; Female; Heart; Heart Valve Diseases - surgery; Heart Valve Prosthesis - adverse effects; Heart Valve Prosthesis - mortality; Hemorrhage - epidemiology; Humans; Incidence; Male; Medical sciences; Middle Aged; Mitral Valve - surgery; Prosthesis Failure; Survival Rate; Thrombosis - diagnosis; Thrombosis - epidemiology; Thrombosis - surgery; Prognosis; Heart valve; Cardiac valvular disease; Surgery
• ISSN: 1010-7940; 1873-734X
• DOI: 10.1016/1010-7940(88)90012-7

The mechanical valve produced by Sorin is a modified tilting discdevice. Between March 1979 and November 1985, 763 Sorin prostheses wereimplanted in 710 patients. The study has been restricted to 504 isolatedmitral or aortic valves. There were 238 females and 266 males whose agesranged from 2 to 71 years (mean 43.8). Follow-up is 99.23% and covers 1045patient-years. No structural failure has been observed. In the aorticposition, 282 Sorin prostheses were implanted with the large orificeorientated towards the right coronary sinus. Hospital mortality was 5%(14/282). Actuarial survival at 78 months was 94.68% +/- 1.6% with alinearized mortality rate of 1.7% patient-years. There were 11 late deaths(9 valve-related and 2 non valve-related). The linearized rate ofoccurrence of embolic events was 0.32 patient-years (2/268). Actuarialsurvival complication-free at 78 months was 90.88% +/- 2.83%.Preoperatively, 19.8% patients were in NYHA class II, 68.5% in III and11.7% in IV; postoperatively, 79.3% patients were in NYHA class I, 19.5% inII and 1.2% in III. In the mitral position, 222 Sorin prostheses wereimplanted with the large orifice orientated anteriorly in 46 patients(group 1) and posteriorly-in 176 patients (group 2). Hospital mortality was4.5% (10/222). Actuarial survival at 66 months was 93.25% +/- 2.1% with alinearized mortality rate of 2.8 patient- years. There were 12 late deaths(9 valve-related and 3 non valve- related). The 66-month actuarial freedomfrom embolic events was 95.8% +/- 1.89% with a linearized rate ofoccurrence of 1.44 patient- years.