Examples of accreditation of serum and urinary proteins electrophoresis

• Published in: Annales de biologie clinique (Paris) Vol. 78; no. 1; p. 87
• Main Authors: Roubille, Martine, Albinet, Hélène, Baudin, Bruno, Fellahi, Soraya, Gaillard, Olivier, Lombard, Christine, Louvrier, Emmanuel, Plawecki, Maëlle, Vassault, Anne, Piéroni, Laurence
• Format: Journal Article
• Language: English; French
• Published: France 01-02-2020
• Subjects: Accreditation; Blood Chemical Analysis - methods; Blood Chemical Analysis - standards; Blood Proteins - analysis; Blood Proteins - chemistry; Choice Behavior; Diagnostic Tests, Routine - standards; Electrophoresis - methods; Electrophoresis - standards; Humans; Laboratories - standards; Laboratory Proficiency Testing - methods; Proteinuria - diagnosis; Proteinuria - urine; Quality Control; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Surveys and Questionnaires; Urinalysis - methods; Urinalysis - standards; Validation Studies as Topic; accreditation; serum protein; urinary protein; electrophoresis
• ISSN: 1950-6112
• DOI: 10.1684/abc.2020.1527

Serum proteins and urinary proteins electrophoresis are useful biological tests. They are often prescribed for the screening of monoclonal gammopathys and also during follow-up for treatment response. This test can be accredited according to standard NF ISO 15189 since laboratories use analysers and adapted reagents, but there are numerous protocols for the method validation. This paper present the results of a survey proposed in 2019 to biologists by CNBH and SFBC. The aim of this survey is to give biologists a choice among several protocols that have been positively evaluated by COFRAC.