Active Giant Cell Vasculitis Diagnosis with [.sup.68]Ga PSMA PET/CT Imaging/[.sup.68]Ga PSMA PET/BT Goruntuleme ile Aktif Dev Hucreli Vaskulit Teshisi

• Published in: Molecular imaging and radionuclide therapy Vol. 30; no. 1; p. 57
• Main Authors: Sager, Muhammet Sait, Bilgic, Seckin, Uslu, Lebriz, Asa, Sertaç, Sager, Gunes, Sonmezoglu, Kerim
• Format: Journal Article
• Language: English
• Published: Galenos Yayinevi Tic. Ltd 01-02-2021
• Subjects: Care and treatment; CT imaging; Diagnosis; Genetic aspects; Giant cell arteritis; Health aspects; PET imaging; Prostate-specific antigen; Turkey
• ISSN: 2146-1414
• DOI: 10.4274/mirt.galenos.2019.90532

Vasculitis is a multisystem disease characterized by inflammation with infiltration of leukocytes into the blood vessels. Giant cell arteritis (GCA) is the most common form of vasculitis that mostly affects medium- and large-sized arteries. [.sup.18]Fluorine-fluorodeoxyglucose ([.sup.18]F-FDG) positron emission tomography/computed tomography (PET/CT) is increasingly used to diagnose inflammation of large arteries in GCA. Galium-68 prostate-specific membrane antigen (PSMA) PET/CT has a vital role in the assessment of patients with prostate cancer for recurrence and metastasis of the disease. Various benign and non-prostate malignant conditions may give rise to increased PSMA uptake. Herein, we demonstrate that PSMA uptake can be seen in GCA. Keywords: Vasculitis, GCA, PSMA PET, [.sup.18]F-FDG PET Vaskülit, lökositlerin kan damarlarina infiltrasyonu sonucunda iltihaplanma ile karakterize multisistemik bir hastaliktir. Dev hücreli arterit (DHA), çogunlukla orta büyüklükte ve büyük arterleri etkileyen en yaygin vaskülit seklidir. [.sup.18]Flor-florodeoksiglukoz ([.sup.18]F-FDG) pozitron emisyon tomografi/bilgisayarli tomografi (PET/BT), DHA tanisinda yaygin olarak kullanilir. Galyum-68 prostat spesifik membran antijeni (PSMA) PET/BT, nüks ve metastatik hastaligi olan prostat kanseri hastalarinin degerlendirilmesinde önemli bir role sahiptir. PSMA tutulumuna neden olabilecek çesitli iyi huylu ve prostat disi malign durumlar görülebilmektedir. Bu olgu ile büyük damar vaskülitinde PSMA tutulumunu görülebilecegini göstermek istedik. Anahtar kelimeler: Vaskülit, DHA, PSMA PET, [.sup.18]F-FDG PET