The importance of uterosacral ligament anatomy in overactive bladder: A preliminary study/Asiri aktif mesanede uterosakral ligament anatomisinin onemi: On calisma

• Published in: Turkish journal of obstetrics and gynecology Vol. 15; no. 1; p. 65
• Main Authors: Adiguzel, Cevdet, Yilmaz, Esra Selver Saygili, Arlier, Sefa, Seyfettinoglu, Sevtap, Soker, Gokhan, Uysal, Gulsum, Yucel, Oguz, Sivaslioglu, Akin
• Format: Journal Article
• Language: English
• Published: Galenos Yayinevi Tic. Ltd 01-03-2018
• Subjects: Development and progression; Health aspects; Physiological aspects; Risk factors; Urinary incontinence; Urogenital system; Turkey
• ISSN: 2149-9322
• DOI: 10.4274/tjod.73669

Objective: To evaluate whether uterosacral ligament (USL) thickness measured using magnetic resonance imaging (MRI) was associated with overactive bladder (OAB) in otherwise healthy women. Materials and Methods: The study comprised 27 women with OAB and 27 healthy women (control group) who were followed up at the Obstetrics and Gynecology Department of a tertiary referral center. All subjects were evaluated using pelvic MRI to determine the transverse USL thickness. These measurements were compared between the two groups. p values less than 0.05 were considered statistically significant. Results: The mean age of women in the OAB and control groups were 43.88[+ or -]9.36 years and 39.92[+ or -]5.36 years, respectively. The mean body mass index in the OAB group was 29.77[+ or -]4.82 kg/[m.sup.2] and 27.49[+ or -]3.44 kg/[m.sup.2] in the control group. In the comparison of Pelvic Organ Prolapse Quantification system stages between the groups, no statistically significant relationship was determined. In the OAB group, the mean right USL thickness was 2.04[+ or -]0.34 mm, and the mean left USL was 2.04[+ or -]0.52 mm. In the control group, the mean right USL thickness was 2.17[+ or -]0.47 mm, and the mean left USL was 2.09[+ or -]0.51 mm. There were no statistically significant differences in terms of USL thickness between the OAB and control groups (p>0.05). Conclusion: No previous studies have been identified in the literature that have investigated the relationship between USL thicknesses and urinary incontinence. In the present study, no significant relationship could be demonstrated between right and left USL thicknesses of the OAB and control groups. This was a preliminary study, and further research with larger sample sizes is required to reach a final conclusion. Keywords: Integral theory, magnetic resonance imaging, overactive bladder, uterosacral ligaments Amac: Asiri aktif mesane (AAM) tanisi alan kadinlarda manyetik rezonans goruntuleme (MRG) ile olculen uterosakral ligament (USL) kalinliklarinin, saglikli kadinlarda asiri aktif mesane (OAB) ile iliskili olup olmadigini degerlendirmek. Gerec ve Yontemler: Calismaya, Ocak 2013-Aralik 2015 tarihleri arasinda jinekoloji polikliniginde takip edilen, yaslari 21-55 arasinda degisen, AAM tanili 27 ve saglikli 27 kadin (kontrol grubu) dahil edildi. Tum olgular, transvers USL kalinligini belirlemek icin pelvik MR ile degerlendirildi. Bu olcumler iki grup arasinda karsilastirildi. P degerlerinin 0,05'ten kucuk olmasi istatistiksel olarak anlamli kabul edildi. Bulgular: OAB ve kontrol grubundaki kadinlarin yas ortalamasi sirasiyla 43,88[+ or -]9,36 yil ve 39,92[+ or -]5,36 yil idi. Kontrol grubunda OAB grubunda ortalama vucut kitle indeksi 29,77[+ or -]4,82 kg/[m.sup.2] ve 27,49[+ or -]3,44 kg/[m.sup.2] bulundu. Pelvik Organ Prolapsus Kantifikasyon sistem evrelerinin gruplar arasinda karsilastirilmasinda istatistiksel olarak anlamli bir iliski saptanmadi. OAB grubunda ortalama sag USL kalinligi 2,04[+ or -]0,34 mm, sol USL degeri 2,04[+ or -]0,52 mm idi. Kontrol grubunda sag USL kalinligi 2,17[+ or -]0,47 mm idi ve sol USL degeri 2,09[+ or -]0,51 mm idi. OAB ve kontrol gruplari arasinda USL kalinligi acisindan istatistiksel olarak anlamli farklilik yoktu (p>0,05). Sonuc: Literaturde USL kalinliklarinin uriner inkontinans ile iliskisini inceleyen bir calisma yoktur. Arastirmamizda, AAM ile sag ve sol USL kalinliklari arasinda istatistiksel olarak anlamli bir iliski bulunmadi (p>0,05). Bu calismada OAB ve kontrol gruplarinin sag ve sol USL kalinliklari arasinda anlamli bir iliski gosterilemedi. Bu bir on calisma niteliginde olup, kesin bir sonuca varilabilmesi icin daha cok olgu iceren arastirmalara ihtiyac vardir. Anahtar Kelimeler: Integral teori, manyetik rezonans goruntuleme, asiri aktif mesane, uterosakral ligamentler PRECIS: No difference was identified in terms of right and left USL thicknesses of the OAB and control groups. This was a preliminary study, and further research with larger sample sizes is required to reach a conclusion.