Infective Endocarditis Due to Brucella canis: A Case Report/ Brucella canis'in Neden Oldugu Infektif Endokardit: Bir Olgu Sunumu

• Published in: KLIMIK dergisi Vol. 29; no. 3; p. 138
• Main Authors: Karasahin, Omer, Iba-Yilmaz, Sibel, Aslan, Mehtap Hulya, Celik, Neslihan
• Format: Journal Article
• Language: English
• Published: AVES 01-12-2016
• Subjects: Brucellosis; Care and treatment; Case studies; Complications and side effects; Development and progression; Infective endocarditis
• ISSN: 1301-143X
• DOI: 10.5152/kd.2016.34

In this report, a case of infective endocarditis due to Brucella canis treated with antibiotics successfully in a 33-year-old man, having a history of rheumatic heart disease and raising animals, admitted with complaints of fever with chills, generalized myalgias, sweating and weakness was presented. Standard tube agglutination (STA) test was negative despite further dilutions to exclude prozone phenomenon. STA test repeated remained negative. Blood culture yielded Brucella spp. B. canis microagglutination test was detected to be positive in 1/160 dilution. A vegetation with dimensions of 0.5 x 0.7 cm detected on aortic valve echocardiographically became smaller after one month of doxycycline, rifampin, and streptomycin treatment, and was undetectable in second month. Repeat echocardiographic examination in the third month revealed no vegetation again, and treatment continued with doxycycline, rifampin and trimethoprim-sulfamethoxazole during outpatient period, and total duration of treatment was planned to be at least one year. Klimik Dergisi 2016; 29(3); 138-41. Key Words: Brucella canis, endocarditis. Bu bildiride, yuksek ates, usume, titreme, yaygin vucut agrisi, terleme ve halsizlik yakinmalariyla basvuran, romatizmal kalp hastaligi oykusu olan ve hayvancilik yapan 33 yasinda bir erkek hastadaki antibiyotiklerle basariyla tedavi edilen Brucella canis'e bagli bir infektif endokardit olgusu sunuldu. Hastanin Brucella standard tup aglutinasyon testi (STA) prozon olayini dislamak icin dilusyonlarin artirilmasina karsin negatifti. Olasi blokan antikorlara yonelik olarak Coombs antiserumuyla yinelenen STA testi de negatif sonuclandi. Hastanin kan kulturunde Brucella spp. uredi. B. canis mikroaglutinasyon testi 1/160 titrede pozitif olarak saptandi. Aort kapaginda ekokardiyografik olarak gozlenen 0.5 x 0.7 cm boyutlarindaki vejetasyon, doksisiklin, rifampisin ve streptomisin tedavisinin birinci ayinda kuculmeye basladi ve ikinci ayda saptanmadi. Ucuncu ayindaki ekokardiyografi kontrolunde de vejetasyon saptanmayan hastanin ayaktan takibi sirasindaki tedavisi, doksisiklin, rifampisin ve trimetoprim-sulfametoksazolle surduruldu ve toplam tedavi suresinin en az bir yil olmasi planlandi. Klimik Dergisi 2016; 29(3); 138-41. Anahtar Sozcukler: Brucella canis, endokardit.