Acute pancreatitis after a course of clarithromycin

We present a case of acute pancreatitis after a course of clarithromycin. An 84-year-old woman died of suspected pneumonia and cardiac failure. Autopsy surprisingly revealed acute pancreatitis. Except for the use of clarithromycin no other cause for her acute pancreatitis was obvious. Pancreatitis i...

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Bibliographic Details
Published in:	Netherlands journal of medicine Vol. 61; no. 7; pp. 266 - 267
Main Authors:	SCHOUWENBERG, B. J. J. W, DEINUM, J
Format:	Journal Article
Language:	English
Published:	Alphen aan den Rijn Van zuiden 01-07-2003
Subjects:	Acute Disease Aged Aged, 80 and over Anti-Bacterial Agents - adverse effects Biological and medical sciences Clarithromycin - adverse effects Drug toxicity and drugs side effects treatment Female Humans Medical sciences Pancreatitis - chemically induced Pharmacology. Drug treatments Toxicity: digestive system Human Case study Antibiotic Clarithromycin Toxicity Acute Pancreatitis Digestive diseases Antibacterial agent Macrolide Elderly Pancreatic disease
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Summary:	We present a case of acute pancreatitis after a course of clarithromycin. An 84-year-old woman died of suspected pneumonia and cardiac failure. Autopsy surprisingly revealed acute pancreatitis. Except for the use of clarithromycin no other cause for her acute pancreatitis was obvious. Pancreatitis induced by clarithromycin has been reported twice in the English literature so far. There are, however, a few reports on acute pancreatitis associated with other macrolide antibiotics, such as erythromycin and roxithromycin.
ISSN:	0300-2977 1872-9061