Ectopic ACTH syndrome in a patient with Crohn's disease

We present the case of a 62-year-old man with Crohn's disease who consulted for abdominal pain and lower limbs edema. The patient developed Cushing's syndrome due to ectopic secretion of ACTH. Diagnostic imaging tests showed multiple metastatic liver lesions and asymmetric thickening of th...

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Bibliographic Details
Published in:	Revista española de enfermedades digestivas Vol. 114; no. 11; p. 690
Main Authors:	Pérez Ramírez, Alberto, Moreno Loro, Antonio, Mohigefer Barrera, Javier, Herrera Justiniano, José Manuel
Format:	Journal Article
Language:	English Spanish
Published:	Spain Sociedad Espanola de Patologia Digestivas 01-11-2022
Online Access:	Get full text
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Summary:	We present the case of a 62-year-old man with Crohn's disease who consulted for abdominal pain and lower limbs edema. The patient developed Cushing's syndrome due to ectopic secretion of ACTH. Diagnostic imaging tests showed multiple metastatic liver lesions and asymmetric thickening of the ileum, that was suspected as the primary tumor. This tumor produced destabilizing gastrointestinal bleeding and an urgent surgical resection was performed. The histopathological study of the resection specimen confirmed a grade 3 neuroendocrine tumor.
ISSN:	1130-0108
DOI:	10.17235/reed.2022.8825/2022