DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses

DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses

New insights into APOBEC editing functions suggest this family of enzymes might protect against invasive attack by foreign DNA.

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Bibliographic Details
Published in:Nature immunology Vol. 4; no. 7; pp. 641 - 643
Main Authors: Harris, Reuben S, Neuberger, Michael S, Sheehy, Ann M, Craig, Heather M, Malim, Michael H
Format: Journal Article
Language:English
Published: Nature Publishing Group 01-07-2003
Online Access:Get full text
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Description
Summary:New insights into APOBEC editing functions suggest this family of enzymes might protect against invasive attack by foreign DNA.
Bibliography:ObjectType-Article-2
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ISSN:1529-2908
1529-2916
DOI:10.1038/ni0703-641