Ventricular tachycardia-based long QT without hypocalcaemia after use of ibandronic acid

Many drugs are known to cause lengthening of the QT interval. Ibandronic acid is a frequently used agent in the treatment of osteoporosis and is known to cause prolongation of the QT interval due to hypocalcaemia. However, no cases of long QT syndrome associated with ventricular tachycardia (VT) wit...

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Bibliographic Details
Published in:	Cardiovascular journal of South Africa Vol. 24; no. 5; p. e11
Main Authors:	Alihanoglu, Yusuf Izzettin, Uludag, Burcu, Kilic, Ismail Dogu, Eryilmaz, Ufuk, Evrengul, Harun
Format:	Journal Article
Language:	English
Published:	South Africa 23-06-2013
Subjects:	Bone Density Conservation Agents - administration & dosage Bone Density Conservation Agents - adverse effects Diphosphonates - administration & dosage Diphosphonates - adverse effects Echocardiography Electrocardiography - drug effects Female Heart Ventricles - diagnostic imaging Heart Ventricles - pathology Humans Hypocalcemia Middle Aged Osteoporosis - complications Osteoporosis - drug therapy Recovery of Function Tachycardia, Ventricular - complications Tachycardia, Ventricular - diagnosis Tricuspid Valve Insufficiency - diagnosis Tricuspid Valve Insufficiency - etiology Withholding Treatment
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Summary:	Many drugs are known to cause lengthening of the QT interval. Ibandronic acid is a frequently used agent in the treatment of osteoporosis and is known to cause prolongation of the QT interval due to hypocalcaemia. However, no cases of long QT syndrome associated with ventricular tachycardia (VT) with a serum calcium level within the normal limits have been reported in the literature. We report on a case of a VT-based long QT syndrome associated with the use of ibandronic acid.
ISSN:	1680-0745
DOI:	10.5830/CVJA-2013-037