Possible role of gonadal hormones as triggering factors in migraine

There is a large evidence that fluctuating peripheral gonadal hormones can trigger migraine attacks in women. It has been proposed that the main factor involved is a rapid fall in circulating estrogen levels. We have analysed migraine and headache attacks reported in some recent studies involving or...

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Bibliographic Details
Published in:	Functional neurology Vol. 1; no. 4; p. 405
Main Authors:	Horowski, R, Runge, I
Format:	Journal Article
Language:	English
Published:	Italy 01-10-1986
Subjects:	Adult Contraceptives, Oral - adverse effects Double-Blind Method Estrogens - physiology Female Gonadal Steroid Hormones - physiology Humans Migraine Disorders - etiology Migraine Disorders - physiopathology Progesterone - physiology
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Summary:	There is a large evidence that fluctuating peripheral gonadal hormones can trigger migraine attacks in women. It has been proposed that the main factor involved is a rapid fall in circulating estrogen levels. We have analysed migraine and headache attacks reported in some recent studies involving oral contraceptives and propose that also at least in a part of these cases, the withdrawal of the exogenous estrogens initiates the attack. Possible mechanisms are discussed and further studies are proposed.
ISSN:	0393-5264