Separation of [sup.90]Y from [sup.90]Sr using sequential multiple column extraction chromatography

• Published in: Journal of radioanalytical and nuclear chemistry Vol. 300; no. 1; p. 445
• Main Authors: Vyas, Chirag K, Joshirao, Pranav M, Manchanda, Vijay K
• Format: Journal Article
• Language: English
• Published: Springer 01-04-2014
• Subjects: Chromatography; Comparative analysis; Crown ethers; Cytokinins
• ISSN: 0236-5731
• DOI: 10.1007/s10967-014-2982-8

The distribution coefficient measurements on Y(III) and Sr(II) were performed using ditertiarybutyl dicyclohexano 18-crown-6 (Sr-selective resin) and N,N,N', N'-tetraoctyldiglycolamide (Y-selective resin) in HN[O.sub.3], HCl and HCl[O.sub.4] media. Separation factors ([sup.90]Y/[sup.90]Sr) based on distribution coefficient data suggested that perchloric acid is distinctly better medium as compared to nitric acid/hydrochloric acid. The mechanism of extraction changes with the nature and concentration of acid and is responsible for the high selectivity in perchloric acid medium. Sequential column studies were carried out on tracers (radioactive/stable) employing Sr-selective/Y-selective extraction chromatographic resins as stationary phases. The final elution of [sup.90]Y was done in 0.01 M EDTA at pH 4.0 which can be used for clinical applications after radiochemical processing. Keywords [sup.90]Y * Strontium selective resin * Tetraoctyldiglycolamide resin * Distribution coefficient * Extraction chromatography