Clinical signs, diagnosis, and treatment of alkalemia in dogs: 20 cases (1982-1984)

• Published in: Journal of the American Veterinary Medical Association Vol. 192; no. 7; p. 943
• Main Authors: Robinson, E P, Hardy, R M
• Format: Journal Article
• Language: English
• Published: United States 01-04-1988
• Subjects: Acid-Base Imbalance - blood; Acid-Base Imbalance - diagnosis; Acid-Base Imbalance - therapy; Acid-Base Imbalance - veterinary; Alkalosis - blood; Alkalosis - diagnosis; Alkalosis - therapy; Alkalosis - veterinary; Alkalosis, Respiratory - blood; Alkalosis, Respiratory - diagnosis; Alkalosis, Respiratory - therapy; Alkalosis, Respiratory - veterinary; Animals; Blood Gas Analysis - veterinary; Dog Diseases - blood; Dog Diseases - diagnosis; Dog Diseases - therapy; Dogs; Female; Hydrogen-Ion Concentration; Male; Retrospective Studies
• ISSN: 0003-1488

Alkalemia (pH greater than 7.50) was measured in 20 dogs admitted over a 3-year period for various clinical disorders. Alkalemia was detected in only 2.08% of all dogs in which blood pH and blood-gas estimations were made. Thirteen dogs had metabolic alkalosis (HCO3- greater than 24 mEq/L, PCO2 greater than 30 mm of Hg), of which 8 had uncompensated metabolic alkalosis, and of which 5 had partially compensated metabolic alkalosis. Seven dogs had respiratory alkalosis (PCO2 less than 30 mm of Hg, HCO3- less than 24 mEq/L); 4 of these had uncompensated respiratory alkalosis and 3 had partially compensated respiratory alkalosis. Ten dogs had double or triple acid-base abnormalities. Dogs with metabolic alkalosis had a preponderance of clinical signs associated with gastrointestinal disorders (10 dogs). Overzealous administration of sodium bicarbonate or diuretics, in addition to anorexia, polyuria, or hyperbilirubinemia may have contributed to metabolic alkalosis in 8 of the dogs. Most of the dogs in this group had low serum K+ and Cl- values. Two dogs with metabolic alkalosis had PCO2 values greater than 60 mm of Hg, and 1 of these had arterial hypoxemia (PaO2 less than 80 mm of Hg). Treatments included replacement of fluid and electrolytes (Na+, K+, and Cl-), and surgery as indicated (8 dogs). Six dogs with respiratory alkalosis had a variety of airway, pulmonary, or cardiac disorders, and 3 of these had arterial hypoxemia. Two other dogs were excessively ventilated during surgery, and 1 dog had apparent postoperative pain that may have contributed to the respiratory alkalosis.