Studies on the anti-tumour, anti-bacterial, and wound-healing properties of dragon's blood

Three in-vitro assays have been adopted to examine the cytotoxicity and anti-bacterial activity of the blood-red sap of Croton lechleri from Ecuador, and to examine its effect upon the proliferation of endothelial cells. The sap was found not to be cytotoxic. Several simple phenolic compounds and di...

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Bibliographic Details
Published in:	Planta medica Vol. 60; no. 6; p. 541
Main Authors:	Chen, Z P, Cai, Y, Phillipson, J D
Format:	Journal Article
Language:	English
Published:	Germany 01-12-1994
Subjects:	Animals Anti-Infective Agents - pharmacology Antineoplastic Agents, Phytogenic - pharmacology Cattle Cell Division - drug effects DNA Replication - drug effects Endothelium - cytology Endothelium - drug effects Humans Molecular Structure Plant Extracts - pharmacology Tumor Cells, Cultured Wound Healing - drug effects
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Summary:	Three in-vitro assays have been adopted to examine the cytotoxicity and anti-bacterial activity of the blood-red sap of Croton lechleri from Ecuador, and to examine its effect upon the proliferation of endothelial cells. The sap was found not to be cytotoxic. Several simple phenolic compounds and diterpenes showed a potent anti-bacterial activity. The sap has little effect upon the proliferation of endothelial cells, and no single active ingredient was identified. A mechanism for the wound-healing property of the sap has been proposed.
ISSN:	0032-0943
DOI:	10.1055/s-2006-959567