Microfluidics in the Undergraduate Laboratory: Device Fabrication and an Experiment to Mimic Intravascular Gas Embolism

Microfluidics in the Undergraduate Laboratory: Device Fabrication and an Experiment to Mimic Intravascular Gas Embolism

A method to fabricate microfluidic devices and an experimental protocol to model intravascular gas embolism for undergraduate laboratories are presented. The fabrication process details how to produce masters on glass slides; these masters serve as molds to pattern channels in an elastomeric polymer...

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Bibliographic Details
Published in:Chemical engineering education Vol. 44; no. 1
Main Authors: Jablonski, Erin L, Vogel, Brandon M, Cavanagh, Daniel P, Beers, Kathryn L
Format: Journal Article
Language:English
Published: Chemical Engineering Education, Chemical Engineering Division of ASEE 01-12-2010
Subjects:
Chemical Engineering
Engineering Education
Laboratory Experiments
Mechanics (Physics)
Plastics
Science Equipment
Undergraduate Study
Online Access:Get more information
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Summary:A method to fabricate microfluidic devices and an experimental protocol to model intravascular gas embolism for undergraduate laboratories are presented. The fabrication process details how to produce masters on glass slides; these masters serve as molds to pattern channels in an elastomeric polymer that can be adhered to a substrate, resulting in a microfluidic device. This fabrication technique can produce various channel configurations. The gas embolism experiment demonstrates fundamental fluid dynamics phenomena in model vasculature.
ISSN:0009-2479