In vivo confocal microscopic findings in patients with steroid-induced glaucoma after LASIK

• Published in: Ophthalmology (Rochester, Minn.) Vol. 111; no. 4; p. 768
• Main Authors: Cheng, Arthur C K, Law, Ricky W K, Young, Alvin L, Lam, Dennis S C
• Format: Journal Article
• Language: English
• Published: United States 01-04-2004
• Subjects: Adult; Cornea - pathology; Female; Glaucoma - chemically induced; Glaucoma - diagnosis; Glucocorticoids - adverse effects; Humans; Intraocular Pressure; Keratitis - diagnosis; Keratitis - drug therapy; Keratomileusis, Laser In Situ; Microscopy, Confocal; Postoperative Complications; Prednisolone - adverse effects; Prednisolone - analogs & derivatives; Visual Fields
• ISSN: 0161-6420
• DOI: 10.1016/j.ophtha.2003.06.029

To report the confocal microscopic findings of 2 different cases of steroid-induced glaucoma after LASIK.
Observational case report of 2 cases.
Two cases of steroid-induced glaucoma after LASIK were selected. Examination with a white-light tandem slit-scanning confocal microscope was performed in addition to routine slit-lamp biomicroscopy.
In vivo confocal findings at the flap interface.
In both cases, the interfaces were identified at a deeper level than expected. Confocal microscopic examination did not show mononuclear cells and granulocytes typically seen in patients with classic diffuse lamellar keratitis.
Our findings confirm that steroid-induced glaucoma after LASIK is not associated with the collection of inflammatory cells. The treatment option of lowering the intraocular pressure is effective in treating the disease, even without anti-inflammatory medications. Confocal in vivo microscopy is a useful tool to study the course of steroid-induced glaucoma after LASIK in humans.